Darrier disease belong to acantholytic group of disorders with loss of intraepidermal coherence.Darrier disease has an onset in puberty in the form of greasy papules, skin coloured to yellow in nature often progressing to plaques.Sites of predeliction being seborrhic areas of body.Nail abnormalities are a read more constant feature with a V shaped
Objectives To map the Greater Manchester (GM) Child Health Information System network to see if it was a viable source of vaccination data for clinicians working in the PED as a case study.Methods Postprimary care vaccination cga 200 to cga 510 adapter management systems for GM were visualised using a systems mapping approach, with data obtained fr
Astrocytomas are common malignant intracranial tumors that comprise the majority of adult primary central nervous system tumors.MicroRNAs (miRNAs) are small, non-coding RNAs (20-24 nucleotides) that post-transcriptionally modulate gene expression by negatively regulating the stability or translational efficiency of their target mRNAs.In our previou
Several ESAT-6-based vaccines have been widely studied in different animal models, presenting potent ability to induce both cellular and humoral responses.As ESAT-6 is a well-characterized mycobacterial antigen, its capacity to induce immune responses in a nonhuman primate model has been evaluated.The immunization of recombinant ESAT-6 (rESAT-6) in
Triple-negative breast cancer (TNBC) is a breast malignancy with a poor prognosis and limited therapeutic options.Many studies show that TNBC exhibits heterogeneity across clinical, histopathological, and molecular levels.In this review, usc trojans snapback hat we discuss the immunogenic features of TNBC with a focus on immunotherapy and the curre